Adherus
AutoSpray Dural Sealant
Adherus helps provide watertight closure and reduce chances of CSF leaks during cranial and spinal procedures. Even more importantly, it's designed to provide dural closure during the critical phase of dural healing.
Find out moreStrong under pressure
Close effectively with Adherus AutoSpray Dural Sealant, Stryker’s adjunct to standard methods of dural repair.

Low swelling
Hydrogels, by nature, absorb liquid when placed in a solution, which can lead to swelling of the implant. Adherus displayed a dimensional change of only 8% due to water uptake compared to other dural sealant (38%).2
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Long lasting
Adherus maintains significant burst strength above physiological intracranial pressure in an in vitro model. The crosslinker with Adherus AutoSpray Dural Sealant has been designed with an average of 17 crosslinking endpoints to increase strength and minimize swelling.1, 2
- Adheres to collagenous material like the dura for up to 15 days as the dura heals2,3
- Absorbs over approximately 90 days3

Easy set-up and application
Adherus hydrogel is ready to use in 1-minute; it sets in approximately one second and remains where it is applied.3
Additionally, the applicator consists of an integrated air pump, which assists on the application of the hydrogel.

Low swelling
Hydrogels, by nature, absorb liquid when placed in a solution, which can lead to swelling of the implant. Adherus displayed a dimensional change of only 8% due to water uptake compared to other dural sealant (38%).2
Get brochure
Long lasting
Adherus maintains significant burst strength above physiological intracranial pressure in an in vitro model. The crosslinker with Adherus AutoSpray Dural Sealant has been designed with an average of 17 crosslinking endpoints to increase strength and minimize swelling.1, 2
- Adheres to collagenous material like the dura for up to 15 days as the dura heals2,3
- Absorbs over approximately 90 days3

Easy set-up and application
Adherus hydrogel is ready to use in 1-minute; it sets in approximately one second and remains where it is applied.3
Additionally, the applicator consists of an integrated air pump, which assists on the application of the hydrogel.


Clinical outcomes
0%
infection
There were no device related infections and no cases of meningitis among subjects treated with Adherus AutoSpray Dural Sealant in a pivotal randomized controlled trial.4
98%
impermeability
98.4% of patients treated with Adherus did not require a second application of the product intraoperatively to achieve tight closure.4
99%
leak prevention
Adherus was found to have a 99.1% success rate4a at preventing CSF leaks in a 17-center randomized controlled trial.4
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