Adherus
AutoSpray Dural Sealant
Long lasting
Adherus maintains significant burst strength above physiological intracranial pressure in an in vitro model. With an average of 17 cross linking end groups, Adherus has an increased strength.1, 2
- Adheres to the dura during the entire healing period of 13 - 15 days6
- Completely resorbs after 90 - 125 days3
Low swelling
Hydrogels, by nature, absorb liquid when placed in a solution, which can lead to swelling of the implant. Adherus displayed a dimensional change of only 8% due to water uptake compared to other dural sealants (38%).2
Easy set-up and application
Adherus hydrogel is ready to use in 1-minute; it sets in approximately one second and remains where it is applied.3
Additionally, the applicator consists of an integrated air pump, which assists on the application of the hydrogel by:
- Creating an "aerosol" effect on the target spot
- Preventing blockages at the tip


Designed for better patient outcomes
0%
infection
There were no device related infections and no cases of meningitis among subjects treated with Adherus AutoSpray Dural Sealant in a pivotal randomized controlled trial.4
98%
impermeability
98.4% of patients treated with Adherus did not require a second application of the product intraoperatively to achieve tight closure.4
99%
leak prevention
Adherus was found to have a 99.1% success rate4a at preventing CSF leaks in a 17-center randomized controlled trial.4
The value of Adherus
Adherus can help to prevent post-operative CSF leaks and help avoid readmission to hospital and possible re-operations, which may result in economic savings for the institution.4,5
Download the data reflecting its clinical and economical value.
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“Adherus is effective; it reduces CSF leak rates. The application of the product is easy, straightforward and consistent.”
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