Adherus

AutoSpray Dural Sealant

Adherus helps provide watertight closure and reduce chances of CSF leaks during cranial and spinal procedures. Even more importantly, it's designed to provide dural closure during the critical phase of dural healing.

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Strong under pressure

Close effectively with Adherus AutoSpray Dural Sealant, Stryker’s adjunct to standard methods of dural repair.

Low swelling

Hydrogels, by nature, absorb liquid when placed in a solution, which can lead to swelling of the implant. Adherus displayed a dimensional change of only 8% due to water uptake compared to other dural sealant (38%).2

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Long lasting

Adherus maintains significant burst strength above physiological intracranial pressure in an in vitro model. The crosslinker with Adherus AutoSpray Dural Sealant has been designed with an average of 17 crosslinking endpoints to increase strength and minimize swelling.1, 2

  • Adheres to collagenous material like the dura for up to 15 days as the dura heals2,3
  • Absorbs over approximately 90 days3
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Easy set-up and application

Adherus hydrogel is ready to use in 1-minute; it sets in approximately one second and remains where it is applied.3

Additionally, the applicator consists of an integrated air pump, which assists on the application of the hydrogel.

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Low swelling

Hydrogels, by nature, absorb liquid when placed in a solution, which can lead to swelling of the implant. Adherus displayed a dimensional change of only 8% due to water uptake compared to other dural sealant (38%).2

Get brochure

Long lasting

Adherus maintains significant burst strength above physiological intracranial pressure in an in vitro model. The crosslinker with Adherus AutoSpray Dural Sealant has been designed with an average of 17 crosslinking endpoints to increase strength and minimize swelling.1, 2

  • Adheres to collagenous material like the dura for up to 15 days as the dura heals2,3
  • Absorbs over approximately 90 days3
Get brochure

Easy set-up and application

Adherus hydrogel is ready to use in 1-minute; it sets in approximately one second and remains where it is applied.3

Additionally, the applicator consists of an integrated air pump, which assists on the application of the hydrogel.

Get brochure

Clinical outcomes

0%

infection

There were no device related infections and no cases of meningitis among subjects treated with Adherus AutoSpray Dural Sealant in a pivotal randomized controlled trial.4

98%

impermeability

98.4% of patients treated with Adherus did not require a second application of the product intraoperatively to achieve tight closure.4

99%

leak prevention

Adherus was found to have a 99.1% success rate4a at preventing CSF leaks in a 17-center randomized controlled trial.4

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Your options

Adherus AutoSpray and AutoSpray Extended Tip applicators enable direct application of the dural sealant hydrogel without adaptors, delivering a mist spray without requiring any additional components beyond the product itself. Adherus is indicated for Cranial and Spinal procedures.

Adherus AutoSpray
Dural Sealant

Features and benefits:

  • Maintains burst pressure strength above physiological intracranial pressure in an in vitro model1
  • Absorbs over approximately 90 days3
  • Pre-assembled applicator

Adherus Extended Tip
AutoSpray Dural Sealant

Features and benefits:

  • Maintains burst pressure strength above physiological intracranial pressure in an in vitro model1
  • Absorbs over approximately 90 days3
  • Extended tip applicator
  • Extended tip, may enhance access, for example in transsphenoidal and spinal approaches.**

Ordering information

Product code
Description
Quantity
NUS-006
Adherus AutoSpray Dural Sealant
5 units
NUS-009
Adherus AutoSpray ET Dural Sealant
5 units
NUS-009-01
Adherus AutoSpray ET Dural Sealant
1 unit
*Please be advised that the Adherus AutoSpray ET Dural Sealant, 1 unit, is not available for purchase in the Benelux region.
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